Lupus & antiphospholipid syndrome
Multiplicative Impact of Adverse Social Determinants of Health on Outcomes in Lupus Nephritis: A Meta‐analysis and Systematic Review
Authors' conclusion
Adverse SDoH is associated with poor LN outcomes. Having two or more adverse SDoH, specifically in different SDoH domains, had a multiplicative impact leading to worse LN outcomes, widening disparities.
Study context
- Population
- Studies measuring associations between social determinants of health (SDoH) and lupus nephritis (LN) outcomes13 studies in meta-analysis
- Comparison
- Patients with vs without adverse SDoH
- Outcome
- Poor LN outcomes including death, end-stage kidney disease, or CVD
Pooled result
As reported in the abstract
Poor LN outcomes, any adverse SDoH
Pooled odds of poor outcomes higher with any adverse SDoH (fold)
1.47
Further pooled results
Poor LN outcomes by SDoH domain
- Individual domain, fold higher odds
- 1.64
- Health care domain, fold higher odds
- 1.77
Poor LN outcomes with two or more adverse SDoH
- Black patients with public insurance and fragmented care, fold higher odds
- 12
- Multiplicative impact of having two or more adverse SDoH
Original publication
Multiplicative Impact of Adverse Social Determinants of Health on Outcomes in Lupus Nephritis: A Meta‐analysis and Systematic Review. Arthritis Care Res (Hoboken). Published 23 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →