Lupus & antiphospholipid syndrome
An educational tool to improve PREeclamPsia knowledge and Aspirin adheRence in lupus prEgnancies: the PREPARE trial
Primary result · Increase in mean preeclampsia knowledge score (ongoing pregnancies)Result — go to the resultMean difference 1.8 points 95% CI −0.5 to 4.2Authors' conclusion
Women with SLE who received an educational tool had greater improvement in preeclampsia knowledge vs controls.
Study context
- Population
- Pregnant women with SLE up to 17 weeks' gestation
- Participants
- 73 women
- Comparison
- Usual care plus educational tool vs usual care alone
- Interventionn = 38
- Primary endpoint
- Difference in preeclampsia knowledge scores
- Follow-up
- Second-trimester visit
Methodological detailstwo-arm, parallel
- Two-arm
- Parallel
Primary result
As reported in the abstract
Increase in mean preeclampsia knowledge score (ongoing pregnancies)
Mean difference
1.8 points
95% CI −0.5 to 4.2
Change by group
Intervention
4.0
mean · 95% CI 2.4–5.6 · points
Controls
2.0
mean · 95% CI 0.3–3.9 · points
Interventionvs Controls
mean difference 1.8 points (95% CI −0.5 to 4.2)
Further findings
Points
| Outcome | Intervention | Controls | Mean increase (points) (95% CI) | |
|---|---|---|---|---|
| Increase in preeclampsia knowledge score including end-of-pregnancy scores of women with fetal loss (six in each group)More for the intervention | 4.8 (95% CI 3.3–6.9) | 1.9 (95% CI 0.3–3.6) | 2.5 (0.3–4.8) | |
| −20246Difference, points (linear scale) |
| Outcome | Intervention | Controls | Difference (95% CI) | |
|---|---|---|---|---|
| ASA adherence (electronic pharmacy data)Trend for higher adherence | 81% | 65% | 15% (−9 to 37%) | |
| −2002040Difference (linear scale) |
Original publication
An educational tool to improve PREeclamPsia knowledge and Aspirin adheRence in lupus prEgnancies: the PREPARE trial. Rheumatology (Oxford). Published 20 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →