Lupus & antiphospholipid syndrome
Life expectancy and death pattern associated with systemic lupus erythematosus diagnosis in Brazil between 2000 and 2019
Authors' conclusion
SLE patients presented higher mortality compared to the general population matched for sex and age and the main causes associated with death were infection and kidney disease.
Study context
- Population
- Deaths related to SLE in the Brazilian Unified Health System (DATASUS), all Brazilian states, 2000–2019
- Exposure
- SLE deaths vs general population
- Outcome
- Main factors associated with mortality and life expectancy of SLE patients
Methodological detailsnational death data (DATASUS), all Brazilian states
- National death data (DATASUS)
- All Brazilian states
Main finding
As reported in the abstract
- Main causes of death associated with SLE: infection and kidney disease
- Most SLE patients died between 19 and 50 years of age
- Deaths associated with kidney disease proportionally higher than in the general population, with progressive decrease during the period
- Increase in the proportion of deaths due to infections both in SLE and in the general population
Observational data: associations, not effects.
Original publication
Life expectancy and death pattern associated with systemic lupus erythematosus diagnosis in Brazil between 2000 and 2019. Lupus. Published 28 February 2024. doi:10.
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