Systemic sclerosis & Raynaud's
Interleukin-6 serum levels are associated with disease features and cardiovascular risk in patients with systemic sclerosis
Authors' conclusion
IL-6 levels are associated with disease manifestations and cardiovascular risk in patients with SSc.
Study context
- Population
- Patients with systemic sclerosis (SSc)
- Participants
- 53 patients
- Outcome
- Relationship of serum IL-6 with disease characteristics and CV risk (SCORE2)
Methodological detailsmultivariate analysis
- Multivariate analysis
Main finding
As reported in the abstract
Associations of IL-6 levels
- Digital ulcers, calcinosis and anti-Scl70 antibody associated with higher IL-6 levels
- Functional respiratory parameters: significant negative association with IL-6 after correction for covariates
- Systematic Coronary Risk Estimation (SCORE2) CV risk: positive and significant association with circulating IL-6
Observational data: associations, not effects.
Original publication
Interleukin-6 serum levels are associated with disease features and cardiovascular risk in patients with systemic sclerosis. Clin Exp Rheumatol. Published 27 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →