Vasculitis & polymyalgia rheumatica
Incidence and prevalence of ANCA-associated vasculitis in Oslo, Norway, applying different criteria-based case definitions: a population-based cohort study
Authors' conclusion
This population-based study adds new evidence that AAV increases in Europe and indicates that using the ACR/EULAR 2022 criteria shifts cases from GPA to MPA relative to the EMA algorithm, affecting epidemiology estimates.
Study context
- Population
- Adults (aged 18+) in the Oslo area, Norway, 2000–2016 (528,924 adults in 2016)97 incident cases
- Participants
- 133 adults
- Exposure
- Granulomatosis with polyangiitis (GPA) vs microscopic polyangiitis (MPA) vs eosinophilic granulomatosis with polyangiitis (EGPA)
- GPAn = 57
- MPAn = 29
- EGPAn = 9
- Outcome
- Incidence and prevalence of AAV
- Follow-up
- 2000-2016
Methodological detailsICD-10 search of administrative databases, manual chart review, European Medicine Agency (EMA) algorithm and ACR/EULAR 2022 classification criteria
- ICD-10 search of administrative databases
- Manual chart review
- EMA algorithm and ACR/EULAR 2022 classification criteria
Main finding
As reported in the abstract
Mean annual incidence of AAV in adults, per million
- Mean annual incidence of antibody-associated vasculitides (AAV) in adults (per million)
- 12.2
- Prevalence peak, AAV cases/million adults, 2016
- 143.7
Observational data: associations, not effects.
Further findings
Classification of incident cases per ACR/EULAR 2022 criteria
- Classification of incident cases per ACR/EULAR 2022 criteria — Unclassified
- 2
Discordance in AAV case classification, ACR/EULAR 2022 criteria vs EMA algorithm
- Discordance
- 11%
Original publication
Incidence and prevalence of ANCA-associated vasculitis in Oslo, Norway, applying different criteria-based case definitions: a population-based cohort study. RMD Open. Published 5 July 2025. doi:10.
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