Lupus & antiphospholipid syndrome
Implications of the accuracy of diagnostic algorithms for systemic lupus on our understanding of racial disparities in pregnancy outcomes
Authors' conclusion
EMR-derived cohorts of pregnancies in women who are Black, but not White, provided accurate estimations of pregnancy outcomes.
Study context
- Population
- Pregnancies with delivery data (2014–2019) in women with ≥1 SLE ICD9/10 code, academic institutions in the United States (Carolinas Collaborative)
- Participants
- 172 pregnancies
- Exposure
- Black vs White women; Electronic medical record (EMR)-derived vs chart review-confirmed SLE cohorts
- Outcome
- Adverse pregnancy outcomes
Methodological detailsEMR-based, multicentre (academic institutions, Carolinas Collaborative), EMR-based algorithms vs chart review confirmation
- EMR-based
- Multicentre (academic institutions, Carolinas Collaborative)
- EMR-based algorithms vs chart review confirmation
Main finding
As reported in the abstract
Adverse pregnancy outcomes, pregnancies in women with ≥1 ICD9/10 SLE code
40%
Adverse pregnancy outcomes, pregnancies with confirmed SLE
52%
White women: SLE frequently over-diagnosed; adverse pregnancy outcome rates lower in EMR-derived vs confirmed SLE cohorts
40-75%
Black women: over-diagnosis less common; pregnancy outcomes lower in EMR-derived vs confirmed SLE cohorts
12-20%
Observational data: associations, not effects.
Original publication
Implications of the accuracy of diagnostic algorithms for systemic lupus on our understanding of racial disparities in pregnancy outcomes. Rheumatology (Oxford). Published 24 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →