Lupus & antiphospholipid syndrome
Impact of perception of illness on quality of life in juvenile systemic lupus erythematosus
Authors' conclusion
Although disease perception did not correlate with disease activation in jSLE, it significantly impacted patient QoL.
Study context
- Population
- Patients diagnosed with juvenile SLE (jSLE) (SLICC 2012 criteria) between January and November 2023, and their parents32 patients and 32 parents
- Outcome
- Effect of illness perception (B-IPQ) on patient QoL (PedsQL) and parental QoL (WHOQOL-BREF)
Main finding
As reported in the abstract
Correlation of illness perception (B-IPQ) with QoL
- Brief illness perception questionnaire (B-IPQ) vs patient quality of life (QoL): significant negative correlation (poorer QoL with negative illness perceptions), r = −0.576, p < .001
- B-IPQ vs parental QoL: no correlation (p => .05)
Observational data: associations, not effects.
Further findings
Disease activity (SLEDAI-2K) and B-IPQ · last outpatient clinic visit
- Median SLEDAI-2K 2 (0-18)
- SLEDAI-2K not correlated with B-IPQ, r = 0.121, p = .51
Poor QoL prevalence
- Patients with poor QoL (below PedsQL cut-off)
- 56.3%
- Parents with poor QoL for general health (below WHOQOL-BREF cut-off)
- 43.8%
Organ involvement
- Musculoskeletal
- 65.6%
- Mucocutaneous
- 59.4%
- Renal
- 50%
- Hematological
- 50%
- Neuropsychiatric: absent
- 0
Original publication
Impact of perception of illness on quality of life in juvenile systemic lupus erythematosus. Lupus. Published 17 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →