Autoinflammatory & rare systemic diseases
Imaging findings in cardiovascular involvements of IgG4-related disease: a systematic review study
Authors' conclusion
This study evaluated current IgG4-RD articles, revealing a higher prevalence in men and vasculopathy as the most common cardiovascular complication.
Study context
- Population
- Cases of cardiovascular Immunoglobulin G4-related disease (IgG4-RD) in studies reporting detailed cardiovascular imaging findings (PubMed, Scopus, Embase, Web of Science, to 1 September 2023)
- Participants
- 120 cases68 studies
- Outcome
- Imaging findings in IgG4-related cardiovascular disease
Methodological detailsPRISMA guidelines, 60 case reports, 5 case series, 2 cross-sectional, 1 case-control
- PRISMA guidelines
- 60 case reports, 5 case series, 2 cross-sectional, 1 case-control
Pooled result
As reported in the abstract
Cardiovascular imaging findings
- Most common imaging finding: vasculopathy (vessel wall thickening, periarteritis, periaortitis, aortitis, stenosis, ectasia, aneurysm, intramural haemorrhage, fistula, dissection), followed by pericardial involvement and mediastinal masses
- Case series and cross-sectional studies also showed vasculopathy as most common finding on various modalities, including angiography and PET/CT
Further pooled results
Patient characteristics
- Mean age (years)
- 62.8
- Most cases male
- Common initial symptoms: dyspnoea and chest pain
Original publication
Imaging findings in cardiovascular involvements of IgG4-related disease: a systematic review study. Rheumatology (Oxford). Published 13 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →