Autoinflammatory & rare systemic diseases

Is Satoyoshi syndrome an autoimmune disease? A systematic review

Rheumatology (Oxford)Published Systematic review of case reports

Authors' conclusion

Satoyoshi syndrome is associated with other autoimmune diseases and a variety of autoantibodies. Improvement after CS or other immunosuppressant treatment was observed in 90% of cases. These data support an autoimmune aetiology for Satoyoshi syndrome.

Study context

Population
Published Satoyoshi syndrome cases (PubMed, Web of Science, Scopus up to January 2022)57 articles
Participants
77 cases
Outcome
Evidence supporting an autoimmune aetiology: symptoms, associated autoimmune diseases, autoantibodies and response to treatment

Pooled result

As reported in the abstract

Women
59
Mean age at diagnosis
21.2 years
Positive autoantibodies among patients tested (39)
27
Pharmacological treatment reported
50
Improvement after CS or other immunosuppressant treatment
90%

Original publication

Is Satoyoshi syndrome an autoimmune disease? A systematic review. Rheumatology (Oxford). Published 7 February 2023. doi:10.1093/rheumatology/kead067

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