Autoinflammatory & rare systemic diseases
Imaging features and clinical value of 18F-FDG PET/CT for predicting airway involvement in patients with relapsing polychondritis
Authors' conclusion
PET/CT is a valuable tool for RP with airway involvement, particularly in assessing peripheral airway lesions, and PET/CT related parameters are significantly associated with disease patterns, severity, and long-term outcomes.
Study context
- Population
- Relapsing polychondritis (RP) patients with airway involvement who underwent 18F-FDG PET/CT, January 2010 to July 2022
- Participants
- 52 patients
- Outcome
- FDG-avid airway lesions with increased FDG uptake on 18F-FDG PET
Methodological detailsretrospective review, long-term follow-up by questionnaire
- Retrospective review
- Long-term follow-up by questionnaire
Main finding
As reported in the abstract
Patients with FDG-avid airway lesions
94.2%
Patterns of airway involvement identified: focal, multifocal and diffuse
3
Observational data: associations, not effects.
Further findings
Long-term follow-up outcomes
- Deaths during follow-up
- 5
- Deaths related to airway problems
- 2
- Higher FDG uptake predicted worse subjective feeling, but not symptom control or pulmonary function
Original publication
Imaging features and clinical value of 18F-FDG PET/CT for predicting airway involvement in patients with relapsing polychondritis. Arthritis Res Ther. Published 14 October 2023. doi:10.
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