Autoinflammatory & rare systemic diseases
Prognostic value of hypermetabolic bone sarcoidosis observed by 18F-fluorodeoxyglucose positron emission tomography
Authors' conclusion
These results suggest that metabolic bone involvement is associated with more diffuse and more severe sarcoidosis.
Study context
- Population
- Patients with sarcoidosis (WASOG criteria) with at least one 18F-FDG PET/CT scan during follow-up, single centre
- Participants
- 175 patients
- Exposure
- Sarcoidosis with vs without metabolic bone involvement on 18F-FDG PET/CT
- Bone involvementn = 32
- Outcome
- Prevalence of metabolic bone involvement and its prognostic impact
Methodological detailsobservational, comparative, monocentric
- Observational
- Comparative
- Monocentric
Main finding
As reported in the abstract
Metabolic bone involvement of sarcoidosis
Bone involvement
18%
32
Observational data: associations, not effects.
Further findings
Disease extent
- Bone involvement associated with intrathoracic and extrathoracic lymph node involvement and a greater number of organs involved
Treatment
- Bone involvement: more frequently received GC, MTX and TNF-α inhibitors and a greater number of treatments
Relapse
- Relapse occurred sooner with bone involvement
Original publication
Prognostic value of hypermetabolic bone sarcoidosis observed by 18F-fluorodeoxyglucose positron emission tomography. Rheumatology (Oxford). Published 19 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →