Vasculitis & polymyalgia rheumatica
IgA vasculitis nephritis—outcomes in adult-onset disease
Main finding · ESKD at presentationResult — go to the resultχ2 11.6Authors' conclusion
Elderly patients with IgAV are more likely to have ESKD at presentation, but there is no difference in renal survival between age groups, among those presenting with independent renal function.
Study context
- Population
- Adults with renal biopsy-confirmed igA vasculitis (IgAV) nephritismedian follow-up 44 months
- Participants
- 202 adults
- Exposure
- Younger adults vs middle-aged adults vs elderly patients
- Outcome
- Progression to end stage kidney disease (ESKD)
Methodological detailsobservational, multicentre
- Observational
- Multicentre
Main finding
ESKD at presentation
χ2
11.6
P = 0.002
By group
As reported in the abstract
Observational data: associations, not effects.
Further findings
Risk factors for development of end stage kidney disease (ESKD)
- Male gender, Black ethnicity, diabetes, histological chronic renal damage and eGFR < 30 ml/min were risk factors for ESKD
Treatment received
- Received GC
- 68.3%
- Additional immunosuppression
- 56.9%
Original publication
IgA vasculitis nephritis—outcomes in adult-onset disease. Rheumatology (Oxford). Published 25 January 2024. doi:10.
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