Vasculitis & polymyalgia rheumatica

Identification of hub genes and gene modules associated with Behçet's disease by weighted gene co-expression network analysis of neutrophil transcriptome

Clin Exp RheumatolPublished Mechanistic study

Authors' conclusion

Our results reveal novel gene modules and hub genes that are associated with neutrophil activation and dysfunction in BD

Study context

Population
Neutrophils from patients with behçet's disease (BD) and healthy controls
Participants
10 vs 10
Comparison
BD patients vs healthy controls
  • BDn = 10
  • Healthy controlsn = 10reference
Outcome
Co-expression modules associated with BD
Methodological detailsweighted gene co-expression network analysis, neutrophil transcriptome
  • Weighted gene co-expression network analysis
  • Neutrophil transcriptome

Main finding

As reported in the abstract

Co-expression modules with different biological functions
8

Original publication

Identification of hub genes and gene modules associated with Behçet's disease by weighted gene co-expression network analysis of neutrophil transcriptome. Clin Exp Rheumatol. Published 23 October 2023. doi:10.55563/clinexprheumatol/05pc5q

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