Vasculitis & polymyalgia rheumatica
Identification of hub genes and gene modules associated with Behçet's disease by weighted gene co-expression network analysis of neutrophil transcriptome
Authors' conclusion
Our results reveal novel gene modules and hub genes that are associated with neutrophil activation and dysfunction in BD
Study context
- Population
- Neutrophils from patients with behçet's disease (BD) and healthy controls
- Participants
- 10 vs 10
- Comparison
- BD patients vs healthy controls
- BDn = 10
- Healthy controlsn = 10reference
- Outcome
- Co-expression modules associated with BD
Methodological detailsweighted gene co-expression network analysis, neutrophil transcriptome
- Weighted gene co-expression network analysis
- Neutrophil transcriptome
Main finding
As reported in the abstract
- Co-expression modules with different biological functions
- 8
Original publication
Identification of hub genes and gene modules associated with Behçet's disease by weighted gene co-expression network analysis of neutrophil transcriptome. Clin Exp Rheumatol. Published 23 October 2023. doi:10. 55563/ clinexprheumatol/ 05pc5q
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