Vasculitis & polymyalgia rheumatica
The Joint Vasculitis Registry in German-speaking countries (GeVas): subgroup analysis of 266 AAV-patients
Authors' conclusion
Demographic characteristics are comparable to those in other European countries. Differences were found regarding ANCA status, frequencies of organ manifestations, and therapeutic regimens.
Study context
- Population
- Patients with newly diagnosed and relapsing AAV enrolled in the GeVas registry (German-speaking countries), June 2019–October 2022
- Participants
- 266 patients
- Exposure
- New-onset AAV vs Relapsing AAV
- New-onset AAVn = 173
- Relapsing AAVn = 93
- Outcome
- Baseline characteristics
- Follow-up
- Baseline
Methodological detailsbaseline cross-sectional analysis, web-based, multicentre, clinician-driven registry, Recruitment started in June 2019
- Baseline cross-sectional analysis
- Web-based
- Multicentre
- Clinician-driven registry
- Recruitment started in June 2019
Main finding
As reported in the abstract
- New-onset AAV
- 173 (65%)
- Relapsing AAV
- 93 (35%)
- Granulomatosis with polyangiitis (GPA)
- 162 (61%)
- Microscopic polyangiitis (MPA)
- 66 (25%)
- Eosinophilic granulomatosis with polyangiitis (EGPA)
- 36 (13%)
- Renal limited AAV
- 2 (1%)
- Median age, years (IQR)
- 59 (51-70)
- Female
- 130 (51%)
- Anti-neutrophil cytoplasmic antibody (ANCA) positive
- 177; 67%
- Induction: GC
- 247, 93%
- Induction: GC with RTX
- 118, 45%
- Induction: GC with CYC
- 112, 42%
Observational data: associations, not effects.
Original publication
The Joint Vasculitis Registry in German-speaking countries (GeVas): subgroup analysis of 266 AAV-patients. Clin Exp Rheumatol. Published 18 October 2023. doi:10.
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