Vasculitis & polymyalgia rheumatica
Validation of the German version of the ANCA-associated vasculitis patient-reported outcome questionnaire
Authors' conclusion
Our study supports the use of the AAV-PRO (German).
Study context
- Population
- German-speaking AAV patients, rheumatology outpatient clinics, University Hospital Düsseldorf48.5% female
- Participants
- 70 patients
- Outcome
- Psychometric properties of the German AAV-PRO (29 items, six domains, each 0–4)
Methodological detailssingle-centre, psychometric validation
- Single-centre
- Psychometric validation
Main finding
As reported in the abstract
Psychometric properties of AAV-PRO (German)
Good internal consistency in "social and emotional impact", "concerns about the future" and "physical function" (Cronbach's alpha)
≥0.83
Test-retest reliability, all domains (Pearson r)
≥0.8
Observational data: associations, not effects.
Further findings
Symptom burden by sex
- Female patients higher symptom burden across all domains and higher total score (Z)
- −2.55, p=0.011
- Fatigue the most prevalent symptom overall
Original publication
Validation of the German version of the ANCA-associated vasculitis patient-reported outcome questionnaire. Clin Exp Rheumatol. Published 29 August 2025. doi:10. 55563/ clinexprheumatol/ mz2sbf
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