Hypertension as a prominent manifestation secondary to renal artery lesions in pediatric Behcet’s disease
Authors' conclusion
Hypertension in paediatric BD is mainly caused by renal artery involvement.
Study context
- Population
- Paediatric Behcet's disease (BD) patients complicated by hypertension, Children's Hospital Capital Institute of Paediatrics, Jan 2009 to Dec 20226 with hypertension
- Participants
- 65 patients
- Outcome
- Clinical characteristics of paediatric vascular BD complicated by hypertension
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Hypertension among paediatric BD patients
- Complicated by hypertension
- 6 (9.2%)
- Female (of 6 with hypertension)
- 5
- Median age at onset
- 9.8 years
- Median age at diagnosis
- 11.3 years
- Right renal artery involvement (of 6 with hypertension)
- 5
Observational data: associations, not effects.
Further findings
Complications secondary to hypertension
- Cardiac involvement and hypertensive retinopathy
- 3
Treatment
- Biological agents
- 4
- Unsuccessful vascular interventional therapy (severe renal artery stenosis)
- 1
- All with renal artery involvement treated with GC and immunosuppressants
Outcome at follow-up · 3-6 years
- Renal atrophy
- 5
- Stable condition
- 1
Original publication
Hypertension as a prominent manifestation secondary to renal artery lesions in pediatric Behcet’s disease. Pediatr Rheumatol Online J. Published 19 January 2024. doi:10. 1186/ s12969-023-00932-6
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