Pediatric rheumatology

Hypertension as a prominent manifestation secondary to renal artery lesions in pediatric Behcet’s disease

Pediatr Rheumatol Online JPublished Retrospective cohort study

Authors' conclusion

Hypertension in paediatric BD is mainly caused by renal artery involvement.

Study context

Population
Paediatric Behcet's disease (BD) patients complicated by hypertension, Children's Hospital Capital Institute of Paediatrics, Jan 2009 to Dec 20226 with hypertension
Participants
65 patients
Outcome
Clinical characteristics of paediatric vascular BD complicated by hypertension
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Hypertension among paediatric BD patients
Complicated by hypertension
6 (9.2%)
Female (of 6 with hypertension)
5
Median age at onset
9.8 years
Median age at diagnosis
11.3 years
Right renal artery involvement (of 6 with hypertension)
5

Observational data: associations, not effects.

Further findings

Complications secondary to hypertension

Cardiac involvement and hypertensive retinopathy
3

Treatment

Biological agents
4
Unsuccessful vascular interventional therapy (severe renal artery stenosis)
1
  • All with renal artery involvement treated with GC and immunosuppressants

Outcome at follow-up · 3-6 years

Renal atrophy
5
Stable condition
1

Original publication

Hypertension as a prominent manifestation secondary to renal artery lesions in pediatric Behcet’s disease. Pediatr Rheumatol Online J. Published 19 January 2024. doi:10.1186/s12969-023-00932-6

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