Hip geometric parameters are associated with radiographic and clinical hip osteoarthritis: Findings from a cross-sectional study in UK Biobank
Authors' conclusion
Greater FNW and HAL were independently related to an increased risk of radiographic HOA, whereas greater DFH appeared to be protective. Greater FNW was independently associated with HESOA and THR.
Study context
- Population
- UK Biobank participants with left hip DXA scans
- Participants
- 40,312 participants
- Exposure
- DXA-derived hip geometric parameters and hip OA
- Outcome
- Radiographic hip OA
Methodological detailsUK Biobank, logistic regression, Cox proportional hazards model, adjusted for sex, age, height, weight and geometric parameters
- UK Biobank
- Logistic regression
- Cox proportional hazards model
- Adjusted for sex, age, height, weight and geometric parameters
Main finding
As reported in the abstract
Radiographic hip OA, fully adjusted model
Femoral neck width (FNW), OR
2.38
2.18–2.59
Hip axis length (HAL), OR
1.25
1.15–1.36
Diameter of the femoral head (DFH), OR (protective)
0.55
0.50–0.61
Observational data: associations, not effects.
Further findings
Hospital diagnosed hip OA (HESOA)
- FNW, OR (only FNW independently related)
- 2.20 (1.80-2.68)
Total hip replacement
- FNW, HR (only FNW independently related)
- 2.51 (1.89-3.32)
Radiographic hip OA, age and sex-adjusted
- FNW, HAL and DFH related to increased risk
Original publication
Hip geometric parameters are associated with radiographic and clinical hip osteoarthritis: Findings from a cross-sectional study in UK Biobank. Osteoarthritis Cartilage. Published 11 September 2023. doi:10.
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