Global, regional, and national burden of gout in people aged 15–39 years from 1990 to 2021: Trends, cross-country inequalities and forecast to 2035
Authors' conclusion
The gout burden gout in people aged 15-39 years increased with notable inequalities. Despite projected ASRs decreases, overall numbers were likely to increase
Study context
- Population
- People aged 15–39 years, global, regional and national, 1990 to 2021, projections to 2035
- Primary endpoint
- Prevalence, incidence and YLDs of gout (ASRs)
- Follow-up
- 1990 to 2021
Methodological detailsJoinpoint regression, Spearman correlation, slope index of inequality and concentration index, Bayesian age-period-cohort forecast
- Joinpoint regression
- Spearman correlation
- Slope index of inequality and concentration index
- Bayesian age-period-cohort forecast
Primary result
As reported in the abstract
Gout burden, 1990 to 2021
- Burden of gout increased in global, demographic, Global Burden of Diseases (GBD) regional and sociodemographic index (SDI) level
- Males, the 35-39 years subgroup and High-SDI regions had the highest burden
- High-income North America had the highest age-standardized rates (ASRs); East Asia the largest numbers
- Moderate positive correlation between gout burden and SDI for nations
- Both absolute and relative inequalities increased
Further findings
Years lived with disability (YLDs) by risk factor
- Males had higher YLDs due to high body mass index (BMI), females due to kidney dysfunction
Forecast to 2035 · 2020 to 2035
- ASRs predicted to decrease, numbers predicted to rise
Original publication
Global, regional, and national burden of gout in people aged 15–39 years from 1990 to 2021: Trends, cross-country inequalities and forecast to 2035. Joint Bone Spine. Published 26 May 2025. doi:10.
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