Spondyloarthritis & psoriatic arthritis

Global health in axial spondyloarthritis: thresholds for the Assessment of SpondyloArthritis international Society Health Index and the EuroQol score: analysis of the ASAS-PerSpA study

Scand J RheumatolPublished Post-hoc analysis of the cross-sectional ASAS-PerSpA study

Authors' conclusion

ASAS-HI and EQ-5D were highly correlated but did not fully overlap.

Study context

Population
Patients fulfilling ASAS criteria for axial spondyloarthritis (axSpA) (median age 41.0 years, 66.5% men)
Participants
2,651 patients
Comparison
ASAS-HI vs EQ-5D-3L for global health
Primary endpoint
Link between ASAS-HI and EQ-5D scores and EQ-5D thresholds for good and poor GH corresponding to the validated ASAS-HI cut-offs (≤5 and ≥12)

Primary result

As reported in the abstract

Spearman correlation between ASAS-HI and EQ-5D (high)
r = −0.73
Agreement between deciles (moderate), weighted kappa
0.51
ROC AUC (both)
0.86
EQ-5D threshold for good GH
0.69
EQ-5D threshold for poor GH
0.54
Crude concordances
0.80-0.81
Agreement (prevalence-adjusted bias-adjusted kappa)
0.60-0.61

Original publication

Global health in axial spondyloarthritis: thresholds for the Assessment of SpondyloArthritis international Society Health Index and the EuroQol score: analysis of the ASAS-PerSpA study. Scand J Rheumatol. Published 16 December 2024. doi:10.1080/03009742.2024.2424085

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