Spondyloarthritis & psoriatic arthritis
Global health in axial spondyloarthritis: thresholds for the Assessment of SpondyloArthritis international Society Health Index and the EuroQol score: analysis of the ASAS-PerSpA study
Authors' conclusion
ASAS-HI and EQ-5D were highly correlated but did not fully overlap.
Study context
- Population
- Patients fulfilling ASAS criteria for axial spondyloarthritis (axSpA) (median age 41.0 years, 66.5% men)
- Participants
- 2,651 patients
- Comparison
- ASAS-HI vs EQ-5D-3L for global health
- Primary endpoint
- Link between ASAS-HI and EQ-5D scores and EQ-5D thresholds for good and poor GH corresponding to the validated ASAS-HI cut-offs (≤5 and ≥12)
Primary result
As reported in the abstract
- Spearman correlation between ASAS-HI and EQ-5D (high)
- r = −0.73
- Agreement between deciles (moderate), weighted kappa
- 0.51
- ROC AUC (both)
- 0.86
- EQ-5D threshold for good GH
- 0.69
- EQ-5D threshold for poor GH
- 0.54
- Crude concordances
- 0.80-0.81
- Agreement (prevalence-adjusted bias-adjusted kappa)
- 0.60-0.61
Original publication
Global health in axial spondyloarthritis: thresholds for the Assessment of SpondyloArthritis international Society Health Index and the EuroQol score: analysis of the ASAS-PerSpA study. Scand J Rheumatol. Published 16 December 2024. doi:10. 1080/ 03009742. 2024. 2424085
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