Spondyloarthritis & psoriatic arthritis
Comparing the construct validity of measurement instruments for pain and stiffness in patients with axial spondyloartwhritis: cross-sectional analysis in the OASIS cohort
Authors' conclusion
The recommended Assessment of SpondyloArthritis international Society Core Outcome Set (ASAS-COS) pain measurement instrument total back pain BASDAI-Q2 has the best known group discrimination. For MS, the ASAS-COS stiffness measure (MS-severity/duration) performs well although MS-severity even slightly better. Known group discrimination is overall stable across CFs.
Study context
- Population
- Patients with r-axSpA with 8-year data from the OASIS cohort (mean age 54, 71% males)
- Participants
- 85 patients
- Exposure
- Three pain and three morning stiffness measurement instruments, compared on construct validity
- Outcome
- Construct validity: correlation hypotheses and known-group discrimination (SMD across external constructs)
Methodological detailsOASIS cohort, known-group discrimination
- OASIS cohort
- Known-group discrimination
Main finding
As reported in the abstract
BASDAI-Q2
1.87
SMD
Total back pain
1.56
SMD
Back pain at night
1.07
SMD
Morning stiffness (MS)-severity
1.51
SMD
MS-severity/duration
1.39
SMD
MS-duration
1.16
SMD
Observational data: associations, not effects.
Further findings
Influence of contextual factors on known-group discrimination
- Influence of contextual factors (CFs) on known group discrimination was limited
Original publication
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