Spondyloarthritis & psoriatic arthritis
Further Validation of a Questionnaire to Assess Flare in Psoriatic Arthritis: Determination of Cutoff and Longitudinal Change
Authors' conclusion
This study has provided further data on the FLARE questionnaire performance and validity.
Study context
- Population
- Patients with psoriatic arthritis (PsA), ReFLAP study, 14 countries
- Participants
- 147 patients
- Comparison
- Flare vs no flare, defined by FLARE questionnaire cutoff
- Flaren = 61
- Outcome
- Optimal FLARE questionnaire (range 0-10) cutoff for defining a flare, by ROC analysis against patient anchor question
Methodological detailsreanalysis of the ReFLAP longitudinal observational study, 14 countries, ROC curve analysis, patient anchor question
- Reanalysis of the ReFLAP longitudinal observational study
- 14 countries
- ROC curve analysis
- Patient anchor question
Performance
As reported in the abstract
Optimal FLARE questionnaire cutoff · baseline
Optimal score cutoff
4
Sensitivity
0.86
Specificity
0.76
Patient-reported flare at baseline
61
41%
Further findings
Clinical and patient-reported outcomes, flare vs no flare (by cutoff) · baseline
- Patients in flare had significantly worse clinical and patient-reported outcomes
Most frequently affirmed questionnaire items in flare
- Pain, mobility, frustration and fatigue
Change scores in new flare at second visit
- New flare: patient-reported and clinical change scores significantly worse than no flare
Original publication
Further Validation of a Questionnaire to Assess Flare in Psoriatic Arthritis: Determination of Cutoff and Longitudinal Change. J Rheumatol. Published 15 March 2026. doi:10.
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