Spondyloarthritis & psoriatic arthritis
Assessing flares in patients with psoriatic arthritis using questionnaires
Authors' conclusion
PsAID-12 may be used for defining PsA flares.
Study context
- Population
- Patients with psoriatic arthritis (PsA) aged ≥18 years
- Participants
- 150 patients
- Exposure
- FLARE Questionnaire vs PsAID-12 against a stand-alone flare question
- Outcome
- Validation of the FLARE Questionnaire and comparison with PsAID-12 for assessing flares
Methodological detailsvalidation study, ROC curve analysis
- Validation study
- ROC curve analysis
Main finding
As reported in the abstract
Discrimination of self-reported flare (ROC analysis)
| Group | AUC | Sensitivity at cut-off ≥3.13 | Specificity at cut-off ≥3.13 |
|---|---|---|---|
| FLARE Questionnaire | 0.90 (95% CI 0.85 to 0.95) | — not stated in the abstract | — not stated in the abstract |
| PsAID-12 | 0.83 (95% CI 0.76 to 0.90) | 0.72 | 0.79 |
AUC
FLARE Questionnaire0.90 (95% CI 0.85 to 0.95)
PsAID-120.83 (95% CI 0.76 to 0.90)
Sensitivity at cut-off ≥3.13
FLARE Questionnaire— not stated in the abstract
PsAID-120.72
Specificity at cut-off ≥3.13
FLARE Questionnaire— not stated in the abstract
PsAID-120.79
— not stated in the abstract
Observational data: associations, not effects.
Further findings
FLARE Questionnaire internal consistency (Cronbach's α)
- α
- 0.88 (95% CI 0.85 to 0.90)
FLARE Questionnaire test-retest reliability (intraclass correlation coefficient (ICC)), 51 patients, 1 week apart
- ICC
- P < 0.001 0.76 (95% CI 0.59 to 0.87)
Agreement of FLARE Questionnaire cut-off with stand-alone question (Cohen's κ)
- κ (95% CI 0.45 to 0.72), moderate agreement
- 0.59
Original publication
Assessing flares in patients with psoriatic arthritis using questionnaires. RMD Open. Published 8 June 2026. doi:10.
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