Spondyloarthritis & psoriatic arthritis
Association Between Patient Perception of Disease Status and Different Components of the Minimal Disease Activity Criteria in Psoriatic Arthritis
Authors' conclusion
This study suggests strong agreement between MDA status and patient-reported good status irrespective of unmet component.
Study context
- Population
- Adult patients with PsA in the international Remission/Flare in PsA (ReFlaP) study
- Exposure
- Minimal disease activity (MDA) status vs patient-reported disease status
- Outcome
- Whether meeting MDA was perceived as good disease control (patient-reported REM or LDA) regardless of which MDA components were not met
Methodological detailsinternational, secondary analysis of the ReFlaP study
- International
- Secondary analysis of the ReFlaP study
Main finding
As reported in the abstract
Patient-reported good disease status (REM/LDA) among patients meeting MDA
Patients meeting MDA reporting good disease status (remission (REM)/low disease activity (LDA))
88.4%
Specificity of MDA score irrespective of unmet component
> 90%
Observational data: associations, not effects.
Further findings
Most commonly unmet MDA component
- Pain was the most commonly unmet component
Odds of MDA patients reporting poor disease status, by unmet component
- Significant only when pain visual analog score (VAS) < 1 was the unmet component; not supported by the sensitivity analysis
Original publication
Association Between Patient Perception of Disease Status and Different Components of the Minimal Disease Activity Criteria in Psoriatic Arthritis. J Rheumatol. Published 15 January 2025. doi:10.
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