Systemic sclerosis & Raynaud's
Frailty assessment in patients with systemic sclerosis
Authors' conclusion
Over half of SSc patients exhibited frailty, which correlated with both SSc-related organ damage and comorbidities. PC-FI appears to predict death and hospitalisations in SSc patients
Study context
- Population
- Consecutive outpatients with SSc aged over 60 years85 with follow-up
- Participants
- 169 outpatients
- Outcome
- Prevalence of frailty (Primary Care Frailty Index, PC-FI)
Methodological detailsconsecutive outpatients, follow-up of hospitalisations in a subset
- Consecutive outpatients
- Follow-up of hospitalisations in a subset
Main finding
As reported in the abstract
Frailty prevalence (PC-FI)
Frailty
51.3%
Mildly frail
31.9%
Moderately frail
10.7%
Severely frail
7.7%
Observational data: associations, not effects.
Further findings
Factors in frail vs non-frail SSc patients
- Frail patients were older, had longer disease duration, higher Charlson Comorbidity index (CCI), Scleroderma Clinical Trials Consortium Damage Index (SCTC-DI), Sclero-ID and more severe SSc complications
Independent factors associated with Primary Care Frailty Index (PC-FI) scores (multivariate analysis)
- Disease duration and SSc-related organ damage
Death or hospitalisation during follow-up
- Patients who died or were hospitalised were older, with higher PC-FI and CCI; SSc disease activity and damage did not differ significantly
Original publication
Frailty assessment in patients with systemic sclerosis. Clin Exp Rheumatol. Published 12 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →