Lupus & antiphospholipid syndrome
Factors Associated With Adherence of Cervical Cancer Screening in Women With Systemic Lupus Erythematosus
Authors' conclusion
Patients with SLE with high disease activity undergo cervical cancer screening less frequently than those with low disease activity. Perceived barriers to cervical cancer screening are moderately correlated with decreased screening.
Study context
- Population
- Consecutive women aged 21–64 years with systemic lupus erythematosus (SLE)median age 42 years
- Participants
- 130 women
- Exposure
- High vs low SLE disease activity
- Outcome
- Adherence to cervical cancer screening according to current guidelines
Methodological detailsconsecutive enrolment, multivariable logistic regression
- Consecutive enrolment
- Multivariable logistic regression
Main finding
As reported in the abstract
Cervical cancer screening adherence
High SLE disease activity vs Low disease activityOdds ratio (95% CI)P value
Cervical cancer screening adherence
0.59(0.39–0.89)
P = 0.01Adjusted for baseline demographics and drug therapy (multivariable model)
0.25(0.08–0.79)
P = 0.02- Cervical cancer screening adherence rate, all women
- 61.5%
Observational data: associations, not effects.
Further findings
Health Beliefs Model (HBM) constructs correlated with decreased screening
- Increased perceived barriers, r
- −0.30 (P < 0.01)
- Decreased self-efficacy, r
- −0.21 (P = 0.02)
Original publication
Factors Associated With Adherence of Cervical Cancer Screening in Women With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). Published 29 May 2024. doi:10. 1002/ acr. 25355
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