Lupus & antiphospholipid syndrome

Factors Associated With Adherence of Cervical Cancer Screening in Women With Systemic Lupus Erythematosus

Arthritis Care Res (Hoboken)Published Cross-sectional study

Authors' conclusion

Patients with SLE with high disease activity undergo cervical cancer screening less frequently than those with low disease activity. Perceived barriers to cervical cancer screening are moderately correlated with decreased screening.

Study context

Population
Consecutive women aged 21–64 years with systemic lupus erythematosus (SLE)median age 42 years
Participants
130 women
Exposure
High vs low SLE disease activity
Outcome
Adherence to cervical cancer screening according to current guidelines
Methodological detailsconsecutive enrolment, multivariable logistic regression
  • Consecutive enrolment
  • Multivariable logistic regression

Main finding

As reported in the abstract

Cervical cancer screening adherence
High SLE disease activity vs Low disease activityOdds ratio (95% CI)P value
Cervical cancer screening adherence
0.59(0.39–0.89)
P = 0.01
Adjusted for baseline demographics and drug therapy (multivariable model)
0.25(0.08–0.79)
P = 0.02
Cervical cancer screening adherence rate, all women
61.5%

Observational data: associations, not effects.

Further findings

Health Beliefs Model (HBM) constructs correlated with decreased screening

Increased perceived barriers, r
−0.30 (P < 0.01)
Decreased self-efficacy, r
−0.21 (P = 0.02)

Original publication

Factors Associated With Adherence of Cervical Cancer Screening in Women With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). Published 29 May 2024. doi:10.1002/acr.25355

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