Lupus & antiphospholipid syndrome

Cervical cancer screening rates in Korean women of childbearing age with systemic lupus erythematosus

LupusPublished Cross-sectional study

Authors' conclusion

National CCS program is often underutilized by Korean women of childbearing age with SLE, particularly among those with lower income and those of rural residency.

Study context

Population
Korean women aged 20–49 with systemic lupus erythematosus (SLE) and age-matched controls, Korean National Health Insurance Service-National Health Information Database (NHIS-NHID) 2016–2017, eligible for National Health Screening Program (NHSP) in 2018–2019
Participants
10,981 vs 54,905
Exposure
Women with SLE vs age-matched controls
  • SLEn = 10,981
  • Controlsn = 54,905reference
Outcome
Cervical cancer screening (CCS) rate: participation in Papanicolaou test among individuals eligible for NHSP
Follow-up
2018-2019
Methodological detailsnationwide claims database (NHIS-NHID), age-matched controls, randomly selected at a 1:5 ratio, logistic regression
  • Nationwide claims database (NHIS-NHID)
  • Age-matched controls, randomly selected at a 1:5 ratio
  • Logistic regression

Main finding

As reported in the abstract

CCS rate

P < 0.0001

Observational data: associations, not effects.

Further findings

OutcomeSLEControls
CCS uptake, age 40-44 (highest uptake)
OR (95% CI 4.17-6.22)5.09— not stated in the abstract
OR (95% CI 4.26-5.07)— not stated in the abstract4.65
CCS uptake with comorbiditiesMild non-significant decrease among women with SLE
OR (95% CI 0.87-1.04)0.96— not stated in the abstract
OR (95% CI 1.13-1.23)— not stated in the abstract1.18

— not stated in the abstract

Factors associated with cervical cancer screening (CCS) uptake

Younger age, lower income, self-employment or medical aid insurance, and rural residence associated with reduced CCS uptake in both groups

Original publication

Cervical cancer screening rates in Korean women of childbearing age with systemic lupus erythematosus. Lupus. Published 3 October 2025. doi:10.1177/09612033251386086

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