Lupus & antiphospholipid syndrome

Reproductive health knowledge and contraceptive use in never pregnant systemic lupus erythematosus patients: A cross-sectional survey

LupusPublished Cross-sectional study

Authors' conclusion

Knowledge of reproductive health, particularly contraceptive use in SLE patients, remains suboptimum.

Study context

Population
Systemic lupus erythematosus (SLE) patients aged 18–50 years, menstruating, never pregnant, Chiang Mai University Hospital, November 2021–July 2023mean age 30.91 years
Participants
204 patients
Outcome
Knowledge of reproductive health (pregnancy and contraception)
Methodological detailssurvey
  • Survey

Main finding

As reported in the abstract

Adequate reproductive health knowledge

Adequate knowledge of pregnancy in SLE

83.82%

Adequate knowledge of contraception in SLE

57.53%

Observational data: associations, not effects.

Further findings

Contraceptive use, past vs current (91 currently sexually active patients)

Male condoms, past to current (p = .007)
76.92% to 62.64%
Withdrawal, past to current (p = .020)
47.25% to 37.36%
Oral contraceptive pills, past to current (p < .001)
19.78% to 2.20%
Medroxyprogesterone acetate injections, past to current (p = .046)
8.79% to 4.40%
No contraception at all, past to current (p = .025)
2.20% to 7.69%
None of the patients used intrauterine devices
0
  • Among 101 patients with sexual experience, 91 (43.96%), currently active, provided their contraceptive practice

Living vs not living with partner

No difference in contraceptive methods, frequency of sexual activity, and SLE disease activity

Original publication

Reproductive health knowledge and contraceptive use in never pregnant systemic lupus erythematosus patients: A cross-sectional survey. Lupus. Published 3 October 2025. doi:10.1177/09612033251386677

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