Lupus & antiphospholipid syndrome
Describing flares: a mixed methods study comparing patient and clinician perspectives in systemic lupus erythematosus and other rheumatic diseases
Authors' conclusion
We highlight differences in how SARD patients and clinicians describe flares, notably related to onset, recognition and intervention.
Study context
- Population
- Patients with SLE and other systemic autoimmune rheumatic diseases (SARDs), and clinicians; international surveysurvey 443 SLE patients, 258 clinicians
- Exposure
- Patient vs clinician perspectives of flares
- Outcome
- Differences in patient vs clinician ratings of flare statements
Methodological detailsinternational co-produced survey, in-depth interviews, thematic analysis, triangulation
- International co-produced survey
- In-depth interviews
- Thematic analysis
- Triangulation
Main finding
As reported in the abstract
Significantly different mean ratings for flare statements
12 of 17
Observational data: associations, not effects.
Further findings
Flares 'often' or 'always' started within minutes or hours
P < 0.001
Original publication
Describing flares: a mixed methods study comparing patient and clinician perspectives in systemic lupus erythematosus and other rheumatic diseases. Rheumatology (Oxford). Published 20 August 2026. doi:10.
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