Lupus & antiphospholipid syndrome
Attribution of neuropsychiatric symptoms and prioritization of evidence in the diagnosis of neuropsychiatric lupus: mixed methods analysis of patient and clinician perspectives from the international INSPIRE study
Authors' conclusion
NPSLE diagnostic tests and clinician assessments have numerous limitations, particularly in detecting diffuse neuropsychiatric symptoms that can be directly attributable and benefit from immunosuppression.
Study context
- Population
- Clinicians and SLE patients in the international INSPIRE study
- Comparison
- Patient vs clinician perspectives on attribution of neuropsychiatric symptoms in SLE
- Outcome
- Attribution of neuropsychiatric symptoms and prioritization of evidence in NPSLE diagnosis
Methodological detailsthematic and comparative analyses, surveys and interviews, international
- Thematic and comparative analyses
- Surveys and interviews
- International
Main finding
As reported in the abstract
Patients reporting never/rarely having been asked if their SLE was flaring
46%
Patients reporting self-assessment of disease activity never/rarely concordant with their clinicians
24%
Original publication
Attribution of neuropsychiatric symptoms and prioritization of evidence in the diagnosis of neuropsychiatric lupus: mixed methods analysis of patient and clinician perspectives from the international INSPIRE study. Rheumatology (Oxford). Published 18 December 2023. doi:10. 1093/ rheumatology/ kead685
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