Lupus & antiphospholipid syndrome

Development and psychometric evaluation of a physician global assessment for type 2 systemic lupus erythematosus symptoms

Lupus Sci MedPublished Psychometric evaluation study

Authors' conclusion

The Type 2 PGA performed well as a physician-reported measure of type 2 SLE symptoms.

Study context

Population
Patients with SLE enrolled in the Duke Lupus Registry; Type 2 PGA rated by six rheumatologists of one academic lupus clinic6 rheumatologists
Participants
263 patients
Outcome
Psychometric performance of the Type 2 PGA
Methodological detailssingle academic lupus clinic, prospectively collected registry data, consensus roundtable, Roundtable discussion to establish consensus guidelines for scoring the Type 2 PGA
  • Single academic lupus clinic
  • Prospectively collected registry data
  • Consensus roundtable
  • Roundtable discussion to establish consensus guidelines for scoring the Type 2 PGA

Recommendations

As reported in the abstract

Intra-rater and inter-rater reliability (intraclass correlation coefficient)
0.83
Correlation with patient-reported polysymptomatic distress (r)
0.76
Correlation with patient-reported fatigue (r)
0.68
Correlation with patient-reported cognitive dysfunction (r)
0.63
Correlation with patient-reported waking unrefreshed (r)
0.62
Correlation with patient-reported forgetfulness (r)
0.60

Original publication

Development and psychometric evaluation of a physician global assessment for type 2 systemic lupus erythematosus symptoms. Lupus Sci Med. Published 17 December 2023. doi:10.1136/lupus-2023-001016

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