Lupus & antiphospholipid syndrome
Factors affecting discrepancies in disease activity evaluation between patients and physicians in systemic lupus erythematosus-The importance of symptoms such as fatigue
Authors' conclusion
Pt-VAS scores tended to be higher than Ph-VAS scores, and the discrepancy was influenced mainly by fatigue. Higher dif (Pt-VAS-Ph-VAS) was associated with lower patient QOL.
Study context
- Population
- Systemic Lupus Erythematosus (SLE) outpatients of the Kyoto Lupus Cohort at Kyoto University Hospital, 2019
- Participants
- 225 outpatients
- Exposure
- Patient VAS vs physician VAS of SLE disease activity
- Outcome
- Discrepancy between Pt-VAS and physician visual analogue scale (Ph-VAS) disease activity scores and factors correlated with it
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Disease activity VAS score
P < 0.001
Observational data: associations, not effects.
Further findings
Correlation of SSC score with patient VAS (Pt-VAS) and dif (Pt-VAS-Ph-VAS)
- SSC score significantly correlated with Pt-VAS and dif (Pt-VAS-Ph-VAS) (p < 0.001)
SSC items correlated with dif (Pt-VAS-Ph-VAS)
- Fatigue showed the most significant correlation with dif (Pt-VAS-Ph-VAS)
Quality of life (QOL) (SF-36, LupusPRO) and dif (Pt-VAS-Ph-VAS)
- Higher dif (Pt-VAS-Ph-VAS) associated with lower QOL by SF-36 and LupusPRO
Original publication
Factors affecting discrepancies in disease activity evaluation between patients and physicians in systemic lupus erythematosus-The importance of symptoms such as fatigue. Lupus. Published 14 September 2024. doi:10.
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