Lupus & antiphospholipid syndrome
Neuromodulation with aerobic exercise reduces fatigue in systemic lupus erythematosus: a randomised, sham-controlled, double-blind study
Authors' conclusion
Despite isolated AEs, there was an improvement in fatigue, however, only tDCS-AE maintained significant and sustained improvement.
Study context
- Population
- Adult female systemic lupus erythematosus (SLE) patients in remission or low disease activity (SLEDAI-2K £4) with significant fatigue (Fatigue Severity Scale (FSS) ≥36 or Modified Fatigue Scale (MFIS) ≥38)
- Participants
- 25 patients
- Comparison
- Transcranial direct current stimulation (tDCS) combined with aerobic exercise vs sham tDCS with aerobic exercise
Methodological detailssham-controlled, double-blind
- Sham-controlled
- Double-blind
Primary result
As reported in the abstract
Fatigue levels · days 30 and 60
- Sustained reduction in fatigue on days 30 and 60 only with tDCS-AE
- p<0.05
Further findings
Pain level, sleep quality, physical activity
- No significant differences
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Neuromodulation with aerobic exercise reduces fatigue in systemic lupus erythematosus: a randomised, sham-controlled, double-blind study. Clin Exp Rheumatol. Published 26 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →