Evaluation of the Diagnostic Performance of American College of Rheumatology, EULAR, and National Institute for Health and Clinical Excellence Criteria Against Clinically Relevant Knee Osteoarthritis: Data From the CHECK Cohort
Authors' conclusion
The diagnoses only moderately overlapped among the three criteria sets.
Study context
- Population
- Symptomatic knees from the Cohort Hip and Cohort Knee (CHECK) study833 knees
- Participants
- 539 participants
- Comparison
- American College of Rheumatology (ACR) vs EULAR vs NICE criteria against experts' diagnosis of clinically relevant knee osteoarthritis (OA)
- Outcome
- Sensitivity, specificity, PPV and NPV of each criteria set against clinically relevant OA (expert diagnosis) as reference standard
- Follow-up
- 5-, 8- and 10-year follow-up
Methodological detailslongitudinal cohort data (5-, 8- and 10-year follow-up), expert diagnosis as reference standard
- Longitudinal cohort data (5-, 8- and 10-year follow-up)
- Expert diagnosis as reference standard
Performance
As reported in the abstract
Diagnostic performance vs clinically relevant OA
- EULAR consistently (F1 through F3) had the highest specificity
- NICE consistently had the highest sensitivity
Further findings
Knees diagnosed with clinically relevant OA by experts
- Knees with clinically relevant OA by experts
- 36%
Agreement among the three criteria sets
- Knees receiving the same diagnosis (OA or non-OA) by all three criteria sets (F1 to F3)
- 67% to 74%
Original publication
Evaluation of the Diagnostic Performance of American College of Rheumatology, EULAR, and National Institute for Health and Clinical Excellence Criteria Against Clinically Relevant Knee Osteoarthritis: Data From the CHECK Cohort. Arthritis Care Res (Hoboken). Published 23 January 2024. doi:10.
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