Two-year clinical follow-up enhances the diagnosis of early-stage hip osteoarthritis: data from check cohort
Authors' conclusion
Final diagnostic criteria, consisting only of the factors obtained through history taking and physical examination, were able to detect early-stage hip OA associated with clinically relevant hip OA 5-10 years later, with 'moderate' precision.
Study context
- Population
- Individuals with hip pain and/or stiffness in primary care, prospective Cohort Hip and Cohort Knee (CHECK) cohort; reference standard: diagnosis of clinically relevant hip osteoarthritis (OA) by 24 experts using 5 to 10 years of follow-up735 symptomatic hips
- Participants
- 543 individuals
- Comparison
- Model of change factors over 2 years vs combined model
- Outcome
- Diagnosis of early-stage hip OA associated with clinically relevant hip OA (AUC)
- Follow-up
- 5-10 years later
Methodological detailsprospective cohort, backward selection, expert diagnosis as reference standard, 24 experts (13 general practitioners, 11 secondary care physicians) set the reference standard
- Prospective cohort
- Backward selection
- Expert diagnosis as reference standard
- 24 experts (13 general practitioners, 11 secondary care physicians) set the reference standard
Performance
As reported in the abstract
AUC of diagnostic models
| Test or model | AUC (SD) |
|---|---|
| Change-factor model | 0.70 (0.01) |
| Combined model | 0.75 (0.01) |
AUC (SD)
Change-factor model0.70 (0.01)
Combined model0.75 (0.01)
- Combined model vs Change-factor model: P < 0.0001 — adding newly defined factors to previously published models significantly increased AUC
Original publication
Two-year clinical follow-up enhances the diagnosis of early-stage hip osteoarthritis: data from check cohort. RMD Open. Published 11 June 2024. doi:10.
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