Osteoarthritis

Hip dysplasia as risk factor for clinically relevant and radiographic hip osteoarthritis: 10-year results from the CHECK cohort

Rheumatology (Oxford)Published Prospective cohort study

Main finding · Clinically relevant hip OAResult — go to the resultOdds ratio 2.80 95% CI 1.15–6.79

Authors' conclusion

In the long term, baseline hip dysplasia was associated with an increased risk for clinically relevant hip OA, but not for incident radiographic hip OA.

Study context

Population
Middle-aged new consulters for hip and/or knee pain (CHECK cohort) with hip pain, available lateral center edge angle (LCEA) and no definite radiographic hip OA (KL grade <2) at baseline; mean age 55.5 (5.4) years, 88% femalehips (251 individuals)
Participants
468 participants
Exposure
Hip dysplasia vs no hip dysplasia
  • Hip dysplasian = 17
Outcome
Clinically relevant hip OA (expert diagnosis on clinical and radiographic data, years 5–10) and incident radiographic hip OA (KL grade ≥2 or total hip replacement)
Follow-up
10 years
Methodological detailship-level analysis, OR adjusted for age, sex and BMI
  • Hip-level analysis
  • OR adjusted for age, sex and BMI

Main finding

Clinically relevant hip OA

Odds ratio

2.80

95% CI 1.15–6.79

Hip dysplasiavs No hip dysplasia
OR 2.80 (95% CI 1.15–6.79)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)
Incident radiographic hip OA · 10 yearsAdjusted for age, sex and BMI0.78 (0.26–2.30)
Prevalence of hip dysplasia at baseline (hip level)
3.6% · 17

Original publication

Hip dysplasia as risk factor for clinically relevant and radiographic hip osteoarthritis: 10-year results from the CHECK cohort. Rheumatology (Oxford). Published 6 December 2023. doi:10.1093/rheumatology/kead650

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