Association between hyperuricaemia and hand osteoarthritis: data from the Xiangya Osteoarthritis Study
Main finding · Prevalence of RHOAResult — go to the resultAdjusted odds ratio 1.34 95% CI 1.11–1.61Authors' conclusion
In this population-based study, hyperuricaemia was associated with a higher prevalence of hand OA.
Study context
- Population
- Participants of the Xiangya osteoarthritis (OA) Study, a community-based observational study
- Participants
- 3,628 participants
- Exposure
- Hyperuricaemia vs normouricaemia
- Outcome
- Radiographic hand OA (RHOA): modified Kellgren-Lawrence grade ≥2 in any hand joint
Methodological detailspopulation-based, community-based, generalised estimating equations
- Population-based
- Community-based
- Generalised estimating equations
Main finding
Prevalence of RHOA
Adjusted odds ratio
1.34
95% CI 1.11–1.61
By group
Hyperuricaemiavs Normouricaemia
aOR 1.34 (95% CI 1.11–1.61)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aOR (95% CI) | |
|---|---|---|
| Bilateral and unilateral RHOAHyperuricaemiavs NormouricaemiaBilateral RHOA | 1.54 (1.18–2.01) | |
| Bilateral and unilateral RHOAHyperuricaemiavs NormouricaemiaUnilateral RHOA | 1.13 (0.89–1.45) | |
| SHOAHigher, although statistically insignificant | 1.39 (0.94–2.07) | |
| 0.512Adjusted odds ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association between hyperuricaemia and hand osteoarthritis: data from the Xiangya Osteoarthritis Study. RMD Open. Published 1 December 2023. doi:10. 1136/ rmdopen-2023-003683
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