Osteoarthritis

Association between hyperuricaemia and hand osteoarthritis: data from the Xiangya Osteoarthritis Study

RMD OpenPublished Cross-sectional study

Main finding · Prevalence of RHOAResult — go to the resultAdjusted odds ratio 1.34 95% CI 1.11–1.61

Authors' conclusion

In this population-based study, hyperuricaemia was associated with a higher prevalence of hand OA.

Study context

Population
Participants of the Xiangya osteoarthritis (OA) Study, a community-based observational study
Participants
3,628 participants
Exposure
Hyperuricaemia vs normouricaemia
Outcome
Radiographic hand OA (RHOA): modified Kellgren-Lawrence grade ≥2 in any hand joint
Methodological detailspopulation-based, community-based, generalised estimating equations
  • Population-based
  • Community-based
  • Generalised estimating equations

Main finding

Prevalence of RHOA

Adjusted odds ratio

1.34

95% CI 1.11–1.61

By group

Hyperuricaemiavs Normouricaemia
aOR 1.34 (95% CI 1.11–1.61)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeaOR (95% CI)
Bilateral and unilateral RHOAHyperuricaemiavs NormouricaemiaBilateral RHOA1.54 (1.18–2.01)
Bilateral and unilateral RHOAHyperuricaemiavs NormouricaemiaUnilateral RHOA1.13 (0.89–1.45)
SHOAHigher, although statistically insignificant1.39 (0.94–2.07)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association between hyperuricaemia and hand osteoarthritis: data from the Xiangya Osteoarthritis Study. RMD Open. Published 1 December 2023. doi:10.1136/rmdopen-2023-003683

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