Acetabular dysplasia and the risk of developing hip osteoarthritis at 2,5,8, and 10 years follow-up in a prospective nationwide cohort study (CHECK).
Authors' conclusion
Baseline AD in individuals between 45 and 65 years is associated with an increased risk of developing RHOA within 2- and 5 years. However, this association seems to weaken after 8 years and disappears after 10 years.
Study context
- Population
- Individuals aged 45–65 from the prospective Cohort Hip and Cohort Knee (CHECK)
- Participants
- 1,002 individuals
- Exposure
- Acetabular dysplasia vs no acetabular dysplasia at baseline
- Outcome
- Incident RHOA (Kellgren & Lawrence (KL) grade ≥2 or total hip replacement (THR)) and end-stage RHOA (KL grade ≥3 or THR)
- Follow-up
- 2, 5, 8 and 10 years
Methodological detailsnationwide, logistic regression with generalized estimating equations
- Nationwide
- Logistic regression with generalized estimating equations
Main finding
As reported in the abstract
Incident RHOA · 2, 5 and 8 years
AD vs No ADOdds ratio (95% CI)
2 years
2.46(1.00–6.04)
5 years
2.28(1.20–4.31)
8 years
1.86(1.22–2.83)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| End-stage RHOA · 5 yearsOnly time point with an association | 3.75 (1.02–13.77) | |
| 0.050.21520Odds ratio (log scale) |
Radiographic hip osteoarthritis (RHOA) · 10 years
- No statistically significant associations between acetabular dysplasia (AD) and RHOA
Original publication
Acetabular dysplasia and the risk of developing hip osteoarthritis at 2,5,8, and 10 years follow-up in a prospective nationwide cohort study (CHECK). Semin Arthritis Rheum. Published 30 March 2023. doi:10.
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