Evaluating Criteria for Symptoms Suggestive of Early Osteoarthritis Over Two Years Post–Anterior Cruciate Ligament Reconstruction: Data From the New Zealand Anterior Cruciate Ligament Registry
Authors' conclusion
Symptoms suggestive of early OA are highly prevalent within two years post-ACLR, with one third of patients experiencing persistent symptoms. These findings indicate that symptoms are more likely to persist rather than newly develop
Study context
- Population
- Patients aged 14 to 40 years in the New Zealand ACL Registry who completed the KOOS at 6, 12 and 24 months post-ACLR
- Participants
- 10,231 patients
- Outcome
- Prevalence of meeting criteria for symptoms suggestive of early osteoarthritis (OA) (≤85% on at least two of four KOOS subscales)
- Follow-up
- 6, 12 and 24 months post-ACLR
Methodological detailsgeneralized estimating equations, multinomial logistic regression
- Generalized estimating equations
- Multinomial logistic regression
Main finding
As reported in the abstract
Prevalence of symptoms suggestive of early OA
Prevalence at 6 months
68%
Prevalence at 12 months
54%
Prevalence at 24 months
46%
Observational data: associations, not effects.
Further findings
Longitudinal patterns of symptom change · 6–24 months post-ACLR
- Persistent symptoms
- 33%
- No symptoms
- 23%
- Symptom resolution
- 29%
- New symptoms
- 6%
- Inconsistent symptoms
- 9%
Odds of symptoms, women (by sex)
- Women consistently showed higher odds of symptoms (OR range)
- 1.17-1.52
Odds of symptoms, older age groups · particularly at 6 months
- Older age groups demonstrated higher odds of symptoms (OR range)
- 1.64-2.45
Original publication
Evaluating Criteria for Symptoms Suggestive of Early Osteoarthritis Over Two Years Post–Anterior Cruciate Ligament Reconstruction: Data From the New Zealand Anterior Cruciate Ligament Registry. Arthritis Care Res (Hoboken). Published 14 November 2024. doi:10.
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