Sustained Limb‐Level Loading: A Ground Reaction Force Phenotype Common to Individuals at High Risk for and Those With Knee Osteoarthritis
Authors' conclusion
Individuals 6 to 12 months post-ACLR exhibit strikingly similar GRF profiles as individuals with KL2 KOA, suggesting both patient groups may benefit from targeted interventions to address aberrant GRF profiles.
Study context
- Population
- Individuals 6–12 months post-ACLR, uninjured matched controls and individuals with knee osteoarthritis (KOA) of differing radiographic severity (KL2–KL4)
- Participants
- 196 individuals
- Exposure
- ACLR 6–12 months post-surgery vs uninjured matched controls and vs KOA KL2, KL3 and KL4
- ACLRn = 36reference
- Uninjured controlsn = 36
- KL2n = 31
- KL3n = 67
- KL4n = 26
- Outcome
- vGRF, apGRF and mlGRF profiles throughout the stance phase of gait
Methodological detailsretrospective, functional linear model
- Retrospective
- Functional linear model
Main finding
As reported in the abstract
GRF profiles through stance, vs ACLR
ACLR lower vGRF and apGRF in early and late stance vs uninjured controls, large effects (Cohen's d range)
1.35-1.66
ACLR greater vGRF than KL2 at 87%-90% of stance; 4.88% BW
d = 0.75
ACLR greater apGRF than KL2 at 84%-94% of stance; 2.41% BW
d = 0.79
Observational data: associations, not effects.
Original publication
Sustained Limb‐Level Loading: A Ground Reaction Force Phenotype Common to Individuals at High Risk for and Those With Knee Osteoarthritis. Arthritis Rheumatol. Published 17 January 2024. doi:10.
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