Clinical, Health‐Related Quality of Life, and Gait Differences Among Obesity Classes in Adults With Knee Osteoarthritis
Authors' conclusion
Among adults with knee OA, those with class III obesity had significantly higher pain levels and worse physical HRQL and gait characteristics compared to adults with overweight or class I or class II obesity.
Study context
- Population
- Older adults (mean age 64.6 years, SD 7.8 years) with knee osteoarthritis (OA) and overweight or obesity
- Participants
- 823 adults
- Exposure
- Class III obesity vs overweight or class I and class II obesity
- Outcome
- WOMAC knee pain (0-20)
Main finding
As reported in the abstract
Class III
8.6
mean
Overweight or class I
7.0
mean
Class II
7.4
mean
Difference (95% CI)P value
Class IIIvs Overweight or class I
1.5(1.0–2.1)
P < 0.0001Class IIIvs Class II
1.1(0.6–1.7)
P = 0.0002Observational data: associations, not effects.
Further findings
Mean
| Outcome | Overweight or class I | Class II | Class III | Difference (95% CI) | P value | |
|---|---|---|---|---|---|---|
| Short Form 36 physical HRQLClass IIIvs Overweight or class I | 37.3 | 35.0 | 31.0 | −6.2 (−7.8 to −4.7) | P < 0.0001 | |
| Short Form 36 physical HRQLClass IIIvs Class II | −3.9 (−5.6 to −2.2) | P < 0.0001 | ||||
| −10−505Difference (linear scale) |
Mean, cm
| Outcome | Overweight or class I | Class II | Class III | Difference (cm) (95% CI) | P value | |
|---|---|---|---|---|---|---|
| Base of support during gaitClass IIIvs Overweight or class I | 11.6 | 11.6 | 14.0 | 3.3 (2.6–4.0) | P < 0.0001 | |
| Base of support during gaitClass IIIvs Class II | 2.4 (1.6–3.2) | P < 0.0001 | ||||
| −20246Difference, cm (linear scale) |
Original publication
Clinical, Health‐Related Quality of Life, and Gait Differences Among Obesity Classes in Adults With Knee Osteoarthritis. Arthritis Care Res (Hoboken). Published 16 January 2024. doi:10.
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