Cost‐Effectiveness of Weight‐Loss Interventions Prior to Total Knee Replacement for Patients With Class III Obesity
Authors' conclusion
For patients with class III obesity considering TKR, RYGB provides good value while immediate TKR without weight loss is not economically efficient.
Study context
- Population
- Knee OA patients with class III obesity (BMI >40 kg/m²) considering total knee replacement (TKR)model-based
- Comparison
- RYGB vs laparoscopic sleeve gastrectomy (LSG) vs lifestyle nonsurgical weight loss vs immediate TKR vs no weight loss/no TKR
- Outcome
- Cost, quality-adjusted life expectancy (QALE) and incremental cost-effectiveness ratios (ICERs), discounted at 3% per year
- Follow-up
- Lifetime
Methodological detailsOsteoarthritis Policy model, health care sector perspective, discounted at 3% per year, deterministic and probabilistic sensitivity analyses
- Osteoarthritis Policy model
- Health care sector perspective
- Discounted at 3% per year
- Deterministic and probabilistic sensitivity analyses
Main finding
As reported in the abstract
Cost-effectiveness
ICER
$10,600/QALY
LSG vs No weight loss/no TKR · quality-adjusted life expectancy (QALE) +1.64 quality-adjusted life-years (QALYs); lifetime medical costs +$17,347
ICER
$20,500/QALY
RYGB vs LSG · QALE +0.22; costs +$4,607
Further findings
TKR utilization
- Relative to immediate TKR, LSG and RYGB delayed and decreased TKR utilization
Probabilistic sensitivity analysis
- RYGB cost-effective in iterations at willingness-to-pay $50,000/QALY
- 67%
Original publication
Cost‐Effectiveness of Weight‐Loss Interventions Prior to Total Knee Replacement for Patients With Class III Obesity. Arthritis Care Res (Hoboken). Published 1 February 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →