Cost‐Effectiveness of Surgical Weight‐Loss Interventions for Patients With Knee Osteoarthritis and Class III Obesity
Authors' conclusion
RYGB offers good value among knee OA patients with BMI ≥40 kg/m2 , while LSG may provide good value among those with BMI between 35 and 41 kg/m2 .
Study context
- Population
- Knee osteoarthritis (OA) patients with BMI ≥40 kg/m² (simulated cohorts)
- Comparison
- Usual care + RYGB and usual care + laparoscopic sleeve gastrectomy (LSG) vs usual care alone
- Outcome
- Quality-adjusted life-years (QALYs), lifetime costs and incremental cost-effectiveness ratios (ICERs), discounted at 3%/year
- Follow-up
- Lifetime
Methodological detailsOsteoarthritis Policy model, health care sector perspective, 3%/year discounting, sensitivity analyses, probabilistic sensitivity analysis, model inputs from published data
- Osteoarthritis Policy model
- Health care sector perspective
- 3%/year discounting
- Sensitivity analyses
- Probabilistic sensitivity analysis
- Model inputs from published data
Main finding
As reported in the abstract
Quality-adjusted life expectancy, lifetime costs and ICER
QALY gain
1.35 years
Usual care + RYGB
Incremental lifetime cost
$7,209
Usual care + RYGB
ICER
$5,300/QALY
Usual care + RYGB
Further findings
Opioid use
TKR usage
| Outcome | Usual care + RYGB | Usual care + LSG | Usual care |
|---|---|---|---|
| Probabilistic sensitivity analysis: cost-effective at WTP $50,000/QALY (% of iterations) | 70% | 30% | — not stated in the abstract |
— not stated in the abstract
Cohorts with BMI 38–41 kg/m² (subgroup)
- Usual care + LSG dominated usual care + RYGB
Original publication
Cost‐Effectiveness of Surgical Weight‐Loss Interventions for Patients With Knee Osteoarthritis and Class III Obesity. Arthritis Care Res (Hoboken). Published 17 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →