Long‐Term Mortality of Patients With Osteoarthritis After Joint Replacement: Prognostic Value of Preoperative and Postoperative Pain and Function
Main finding · Long-term mortality by generic function at 12-month follow-upResult — go to the resultHazard ratio 1.79 95% CI 1.24–2.60Authors' conclusion
Poor function based on the generic assessment was associated with increased long-term mortality, suggesting that functional impairments in daily life activities may be more important for long-term survival than OA-specific impairments in this patient group.
Study context
- Population
- Patients with advanced osteoarthritis (OA) of the hip or knee with unilateral total hip or knee replacement, January 1995–December 1996 (Ulm Osteoarthritis Study)
- Participants
- 706 patients
- Exposure
- Clinically relevant impairment in generic function vs reference
- Outcome
- Long-term mortality (follow-up last updated July 2019)
Methodological detailsCox proportional regression adjusted for covariates
- Cox proportional regression adjusted for covariates
Main finding
As reported in the abstract
Long-term mortality by generic function at 12-month follow-up · 12-month follow-up value
Hazard ratio
1.79
95% CI 1.24–2.60
Clinically relevant impairmentvs Reference
HR 1.79 (95% CI 1.24–2.60)
Observational data: associations, not effects.
Further findings
Pain and function after arthroplasty
- Clear reduction in pain and improved function throughout all assessments
Original publication
Long‐Term Mortality of Patients With Osteoarthritis After Joint Replacement: Prognostic Value of Preoperative and Postoperative Pain and Function. Arthritis Care Res (Hoboken). Published 17 November 2022. doi:10.
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