Loss of Productivity‐Adjusted Life‐Years in Working‐Age Australians Due to Knee Osteoarthritis: A Life‐Table Modeling Approach
Authors' conclusion
Our modeling demonstrates a significant economic burden of KOA among the working Australian population, with marked productivity loss.
Study context
- Population
- Working-age Australians (15–64 years); Knee osteoarthritis (KOA) prevalence from 2019 Global Burden of Diseases study, demographic and mortality data from the Australian Bureau of Statistics
- Comparison
- Working-age Australians with knee OA vs those without knee OA
- KOAn = 913,539
- Outcome
- Productivity burden of knee OA: lost PALYs and lost GDP
- Follow-up
- Retirement age (65 years)
Methodological detailsstatic life-table model, follow-up to 65 years (retirement age), 1-year cycle length, annual discount rate of 5%
- Static life-table model
- Follow-up to 65 years (retirement age)
- 1-year cycle length
- Annual discount rate of 5%
Main finding
As reported in the abstract
Losses attributable to knee OA · By retirement age
- Excess deaths
- 39,602
- Years of life lost
- 125,651
- Quality-adjusted life-years (QALYs) lost
- 1,938,059
- Productivity-adjusted life-years (PALYs) lost
- 1,943,287
- Lost gross domestic product (GDP) (Australian dollars)
- 424 billion
Further findings
Prevalence of knee OA among working-age Australians, 2019
- Overall prevalence
- 5.5%
- Prevalence in men
- 4.5%
- Prevalence in women
- 6.5%
Original publication
Loss of Productivity‐Adjusted Life‐Years in Working‐Age Australians Due to Knee Osteoarthritis: A Life‐Table Modeling Approach. Arthritis Care Res (Hoboken). Published 17 November 2022. doi:10.
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