Systemic sclerosis & Raynaud's
Emphysema elevates the DETECT scores: impact on pulmonary hypertension screening and diagnosis in systemic sclerosis
Authors' conclusion
In SSc, CPFE and emphysema are associated with a higher and more frequently positive DETECT score.
Study context
- Population
- Systemic sclerosis (SSc) patients from a referral centre with chest tomography and data to calculate the DETECT score, without pulmonary hypertension at baseline
- Participants
- 550 eligible cases
- Exposure
- Combined pulmonary fibrosis and emphysema (CPFE), emphysema and interstitial lung disease (ILD) vs their absence, for DETECT score
- Emphyseman = 59
- ILDn = 232
- Outcome
- DETECT score, DETECT score positivity and false positivity
- Follow-up
- Baseline
Methodological detailssingle referral centre, regression models adjusted for selected covariates
- Single referral centre
- Regression models adjusted for selected covariates
Main finding
As reported in the abstract
DETECT score, positivity and false positivity
| Group | Value | Prevalence |
|---|---|---|
| ILD | 42% | |
| Emphysema | 11% | |
| CPFE | 7% | 7% |
Value
ILD42%
Emphysema11%
CPFE7%
Prevalence
ILD— not stated in the abstract
Emphysema— not stated in the abstract
CPFE7%
Observational data: associations, not effects.
Original publication
Emphysema elevates the DETECT scores: impact on pulmonary hypertension screening and diagnosis in systemic sclerosis. Rheumatology (Oxford). Published 1 August 2025. doi:10. 1093/ rheumatology/ keaf410
Composed by AI from the published abstract and checked against it. How Briefs are made →