Systemic sclerosis & Raynaud's
Performance of DETECT Pulmonary Arterial Hypertension Algorithm According to the Hemodynamic Definition of Pulmonary Arterial Hypertension in the 2022 European Society of Cardiology and the European Respiratory Society Guidelines
Authors' conclusion
The performance of the DETECT algorithm to screen for PAH in patients with SSc is maintained when PAH is defined according to the 2022 ESC/ERS hemodynamic definition, indicating that DETECT remains applicable to screen for PAH in patients with SSc.
Study context
- Population
- Patients with systemic sclerosis (SSc) in DETECT
- Participants
- 466 patients
- Comparison
- DETECT pulmonary arterial hypertension (PAH) algorithm performance with PAH per 2022 European Society of Cardiology (ESC)/European Respiratory Society (ERS) definition vs 2014 definition
- Primary endpoint
- Performance (sensitivity, specificity) of DETECT PAH algorithm in identifying patients with high risk of PAH per 2022 ESC/ERS definition
Methodological detailsdiagnostic accuracy, descriptive comparison
- Diagnostic accuracy
- Descriptive comparison
Primary result
As reported in the abstract
DETECT PAH algorithm performance
| Group | Sensitivity | Specificity |
|---|---|---|
| 2022 ESC/ERS definition | 88.2% | 50.8% |
| 2014 definition | 95.8% | 47.8% |
Sensitivity
2022 ESC/ERS definition88.2%
2014 definition95.8%
Specificity
2022 ESC/ERS definition50.8%
2014 definition47.8%
Original publication
Performance of DETECT Pulmonary Arterial Hypertension Algorithm According to the Hemodynamic Definition of Pulmonary Arterial Hypertension in the 2022 European Society of Cardiology and the European Respiratory Society Guidelines. Arthritis Rheumatol. Published 2 April 2024. doi:10.
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