Dry synovitis, a rare entity distinct from juvenile idiopathic arthritis
Authors' conclusion
DS represents a unique juvenile-onset arthropathy, distinct from polyarticular JIA.
Study context
- Population
- Children with dry synovitis (juvenile onset) compared with RF-negative polyarticular JIA
- Exposure
- Dry synovitis vs RF-negative polyarticular JIA
- Dry synovitis (DS)n = 12
- Outcome
- Clinical features vs RFneg-polyJIA
Methodological detailsmulticentre, comparison with RF-negative polyarticular JIA cohort
- Multicentre
- Comparison with RF-negative polyarticular JIA cohort
Main finding
As reported in the abstract
- DS vs RFneg-polyJIA: P = 0.0001
- DS vs RFneg-polyJIA: P = 0.0001
- DS vs RFneg-polyJIA: P = 0.0001
- DS vs RFneg-polyJIA: P = 0.0001
Observational data: associations, not effects.
Further findings
Response to treatment (DS)
- Limited joint mobility
- 11/12
- Need of joint replacement
- 2
- Response variable
- All treated with low-dose corticosteroids and MTX; anti-TNF agents in five
Original publication
Dry synovitis, a rare entity distinct from juvenile idiopathic arthritis. Pediatr Rheumatol Online J. Published 23 January 2023. doi:10. 1186/ s12969-023-00789-9
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