Spondyloarthritis & psoriatic arthritis
Does weather matter? Exploring associations between season and meteorological factors and psoriatic arthritis disease activity
Authors' conclusion
Season was associated with PsA disease activity, being lower in summer. Meteorological factors were not associated with PsA disease activity in our study sample.
Study context
- Population
- Patients with psoriatic arthritis (PsA) from the Dutch South West Psoriatic Arthritis cohort from 2013 to 2023patients with PsA
- Participants
- 935 patients
- Exposure
- Season and meteorological factors and PsA disease activity
- Outcome
- PsA incidence and disease activity (PASDAS and DAPSA) between seasons
- Follow-up
- At diagnosis
Methodological detailsmultivariable analyses
- Multivariable analyses
Main finding
As reported in the abstract
- No significant difference in PsA incidence and disease activity (Psoriatic Arthritis Disease Activity Score (PASDAS) and Disease Activity in Psoriatic Arthritis (DAPSA)) between seasons
Observational data: associations, not effects.
Secondary outcomes
| Outcome | β (95% CI) |
|---|---|
| DAPSA · During follow-upWINTER vs SUMMER · multivariable analyses; higher DAPSA in winter | 2.59 (0.74–4.43) |
| DAPSA · During follow-upSPRING vs SUMMER · multivariable analyses; higher DAPSA in spring | 1.95 (0.001–3.90) |
| DAPSA · During follow-upAUTUMN vs SUMMER · multivariable analyses; higher DAPSA in autumn | 1.93 (0.17–3.69) |
DAPSA subcomponents
- Significantly higher Visual Analog Scale (VAS) patient pain and global assessment in autumn and higher swollen joint count 66 and C-reactive protein in winter compared with summer
PASDAS and mood
- Season was not significantly associated with PASDAS, nor with mood
Meteorological factors and PASDAS and DAPSA
- Meteorological factors were not significantly associated with PASDAS and DAPSA
Original publication
Does weather matter? Exploring associations between season and meteorological factors and psoriatic arthritis disease activity. RMD Open. Published 23 October 2026. doi:10. 1136/ rmdopen-2026-006967
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