Spondyloarthritis & psoriatic arthritis
A Real-World Analysis of Weather Variation on Disease Activity and Patient-Reported Outcomes in Psoriatic Arthritis
Authors' conclusion
Statistically significant differences in clinical profile were evident between winter and summer, as well as in their correlation with weather measurements. However, these distinctions lack clinical significance, suggesting a small impact on patients with PsA.
Study context
- Population
- Patients with psoriatic arthritis (PsA) enrolled in Rhumadata, Montreal, 2015 to 2020
- Participants
- 858 patients2,665 patient-reported outcomes (PROs)
- Exposure
- Winter vs summer; correlation of weather measurements with disease activity (DA) and PROs
- Outcome
- Correlation between weather variation (temperature, relative humidity, pressure), DA and PROs
Methodological detailsreal-world, registry-based (Rhumadata)
- Real-world
- Registry-based (Rhumadata)
Main finding
As reported in the abstract
DA, winter vs summer
- Summer: positive correlations between humidity and symptoms (PGA, fatigue, pain, CRP, BASDAI, BASFI)
- Summer: negative correlations between temperature and HAQ-DI
- Winter: positive correlations between temperature, fatigue and pain
- Winter vs Summer: P = 0.001
- Winter vs Summer: P < 0.001
Observational data: associations, not effects.
Original publication
A Real-World Analysis of Weather Variation on Disease Activity and Patient-Reported Outcomes in Psoriatic Arthritis. J Rheumatol. Published 15 September 2024. doi:10.
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