Spondyloarthritis & psoriatic arthritis
Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study
Authors' conclusion
Lifestyle-related risk factors were prevalent in patients with PsA. The associations among lifestyle-related factors and PsA disease activity, mainly obesity and smoking, provide a foundation to address lifestyle in PsA care.
Study context
- Population
- Patients newly diagnosed with PsA between 2013 and 2023 (Dutch South West Psoriatic Arthritis Study)
- Participants
- 938 patients
- Exposure
- Higher vs lower composite lifestyle risk score
- Outcome
- Disease activity outcomes: PASDAS, DAPSA, PASDAS and DAPSA low disease activity (LDA) and remission, and MDA
- Follow-up
- One year
Methodological detailsmulticentre, multivariable analyses
- Multicentre
- Multivariable analyses
Main finding
As reported in the abstract
Association of higher lifestyle risk score with 1-year disease activity (multivariable) · one-year follow-up
- PASDAS, β
- 0.15 (95% CI 0.08-0.23)
- PASDAS-LDA, OR
- 0.59 (95% CI 0.45-0.77)
- Minimal disease activity (MDA), OR
- 0.72 (95% CI 0.57-0.90)
- Disease activity in PsA (DAPSA), β
- 1.18 (95% CI 0.65-1.71)
- DAPSA-LDA, OR
- 0.74 (95% CI 0.59-0.92)
Observational data: associations, not effects.
Further findings
Prevalence of lifestyle-related factors · baseline
- Obesity
- 33%
- Abdominal obesity
- 51%
- Current smoking
- 19%
- Alcohol consumption
- 72%
- Physically inactive
- 3%
Individual factors · one-year follow-up
- General obesity, abdominal obesity and smoking significantly associated with higher PASDAS and DAPSA and lower odds of PASDAS-LDA and MDA
Original publication
Associations of Lifestyle‐Related Factors and Psoriatic Arthritis Disease Activity: The Dutch South West Psoriatic Arthritis Study. Arthritis Care Res (Hoboken). Published 16 May 2026. doi:10.
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